Siriwantanmetanon n, fiebich bl, efferth t, prieto jm, heinrich m. Anticancer activity of some medicinal plants from high altitude evergreen elements. In vitro anticancer activity of selected medicinal plants. Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer activity of root. The nature of cytotoxic activity is found to be apoptotic rather than necrosis by hoechst test. In a research work to study the anticancer activity of silver nanoparticles derived from seed extract of capsicum sp, the ic 50 values for two different extracts were 60.
Pdf in vitro and in vivo methods for anticancer activity evaluation. Pdf on jan 10, 2017, sadri said and others published in vitro anticancer activity of selected medicinal plants from oman find, read and cite all the research you need on researchgate. In vitro anticancer screening of 24 locally used nigerian medicinal plants saudat adamson fadeyi1,3, olugbeminiyi o fadeyi2,4, adedeji a adejumo5, cosmas okoro2 and elbert lewis myles1 abstract background. The use of medicinal plants has a strong track record of contributing to drug development, and there is abroad consensus that the potential. In fact, the medicinal plants are easily available, cheaper and. In vitro antiviral activity of twentyseven medicinal plant. Evaluation of in vitro antibacterial activity of caralluma. In vitro evaluation of anticancer and antimicrobial activity. Sep 28, 2011 many natural products from plants have been identified to exert anticancer activity. Studies of the in vitro anticancer, antimicrobial and.
Anticancer activity is the effect of natural and synthetic or biological and chemical agents to reverse, suppress or prevent carcinogenic progression. Introduction medicinal plants are used in india from prehistoric time. This present study on antioxidant and in vitro anticancer activity of leaf extract of dica o would be useful in future for isolating the respective active constituent and for yielding a potential drug to mankind in treating cancer without adverse effects. Rahman biotechnology programme leader, school of science and engineering, teesside university, middlesbrough tsba, cleveland, united kingdom. The evaluation of nitric oxide scavenging activity of. Oct 01, 2015 siriwantanmetanon n, fiebich bl, efferth t, prieto jm, heinrich m. Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer. Anti cancer and antiangiogenic activity of essential oils extracts from.
In vitro antiviral activity of twentyseven medicinal. Pdf in vitro anticancer screening of 24 locally used nigerian. In vitro and in vivo methods for anticancer activity evaluation and some indian medicinal plants possessing anticancer properties. Further research required to isolate the pure compound from the bark in future for the preparation of the drug. As per iucn red list version 20162, from 1996 to 2016 numerous medicinal plants with prospective uses are facing risk of extinction due to lack of conservation knowledge, extensive exploitation by pharmaceutical industries, habitat loss and deforestation.
In this study, the ethnomedicinal approach was used to select several medicinal plants native to nigeria, on the basis of their local or traditional uses. Merr leeaceae, is a large evergreen shrub native to tropical india, bangladesh, china, bhutan, and malaysia. In vitro anticancer screening of 24 locally used nigerian medicinal plants. Evaluation of anticancer activity of ochinchinensis. In vitro and in vivo anticancer activity of root extracts of. In vitro and in vivo methods for anticancer activity. In vitro antioxidant and anticancer activity of leea. Cancer is a major public health burden in both developed and developing countries. Many plantderived products have been reported to exhibit potent antitumor activity against several rodent and. Plants that are used as traditional medicine represent a relevant pool for selecting plant candidates that may have anticancer properties. Among plantderived components, essential oils eos from aromatic plants have. The effects of plant leaves extract on cancer cells was studied. Results phytochemical screening confirmed the presence of phytoconstituents like alkaloids, flavonoids, glycosides, phenols, lignins, saponins, sterols, tannins.
Nevertheless, a minority of folkloricly used medicinal plants have been evaluated for their pharmacological activities. The aim of this work was to investigate 26 plants belonging to 17 families collected from a unique place in yemen soqotra island for their in vitro anticancer, antimicrobial and antioxidant activities. Evaluating medicinal plants for anticancer activity. In vitro and in vivo anticancer activity of root extracts of sansevieria liberica gerome and. With the increasing burden of cancer globally, there is a need to find newer anticancer agents. In vitro cytotoxic screening of selected saudi medicinal. In vitro anticancer activity studies the extracellular and intracellular extracts prepared were subjected to in vitro cytotoxicity screening on hela cells by the mtt 34, 5dimethylthiazol2yl2, 5diphenyltetrazolium bromide method. Among the three cell lines u87 have the more activity. Breyerbrandwiijk, medicinal and poisonous plants of south and. The present study was undertaken to evaluate the in vitro anticancer potential of selected medicinal plants. Assessment of selected yemeni medicinal plants for their in. In vitro antioxidant capacities were evaluated via free radical scavenging assays. Assessment of selected yemeni medicinal plants for their. In vitro anticancer screening of 24 locally used nigerian.
Brenan was found to demonstrate potent anti cancer activity in this study exhibiting ic50 0. Sumitra chanda and krunal nagani department of biosciences, saurashtra university, rajkot 360005, gujarat, india. According to world health organisation 2, a medicinal plant is defined as any plant in which, one or more of its organs contain substances that can be used for therapeutic purposes or which are precursors for the synthesis of useful drugs. We investigated the anticancer properties of mainly 3 plant extracts native to israel. The methanolic extracts of forty species of plants traditionally used in saudi arabia for the treatment of a variety of diseases were tested in vitro for. Invitro and invivo antitumor activity of catharanthus roseus. In vitro and in vivo studies on selected medicinal plants 99 cesaratto 2004 and with almost all liver pathologies loguercio and federico, 2003. Issn 23203862 evaluation of anticancer activity of stem. The purpose of this study is to evaluate 33 selected yemeni plants for their in vitro anticancer, antimicrobial, and antioxidant activities. Likewise, the extracts from the seaweed associated bacteria inhibited the growth of the gramnegative bacterium proteus mirabilis12. The mtt assay results were used to evaluate the anticancerous activity of the extract.
In vitro anticancer activity of selected medicinal plants from oman sadri abdullah said1, yahya tamimi2, md. Thomas et al 2011, evaluated the in vitro anticancer activity. Anticancer properties of phytochemicals present in medicinal. In vitro antioxidant and anticancer activity of leea indica.
As per national cancer 34 journal of medicinal plants studies institute nci, usa for anticancer screening on a panel of human cell lines, an ic 50 value of less than 100. With this mindset, we sought to undertake a detailed evaluation of the in vitro and in vivo anticancer activity of a number of israeli whole plant extracts. Many natural products from plants have been identified to exert anticancer activity. Endarachnebinghamiae showed anticancer activity with ic 50 values of 6. The plant extracts of 17 commonly used indian medicinal plants were examined for their possible regulatory effect on nitric oxide no levels using sodium nitroprusside as an no donor in vitro. Natural products discovered from medicinal plants have played an important role in the treatment of cancer. In present investigation the ethanolic extract of argemone mexicana l. Most of the plant extracts tested demonstrated direct scavenging of no and exhibited significant activity. The use of traditional medicine as alternative treatments of cancer was recognized in 1950s by the us national cancer institute nci under the leadership of the late dr. In vitro anticancer activity of aqueous extracts and ethanol extracts of fifteen traditional chinese medicines on human digestive tumor cell lines. The potency of plant extracts to inhibit the cancerous growth was recordedin terms of decrease in. Medicinal plants have been used in the past for the treatment of diseases and continue to be an important reservoir for the development of new drugs. This study was carried out to investigate the antiviral activities of.
Preparations of the plant are commonly used across nigeria for the treatment of inflammatory conditions. In vitro anticancer activity of selected medicinal plants from oman. In vitro propagation of various threatened medicinal plants with anticancer activity. In vitro propagation and conservation of useful endangered. Based on the significantly potent activity of some plants extracts reported here, further studies aimed at mechanism elucidation and bioguided isolation of active anticancer compounds is currently underway. These plants continue to be used against various types of tumours such as sarcoma, lymphoma, carcinoma and leukemia. Comparative phytochemical investigation, antioxidant and. Jan 15, 20 synthesis, characterization, and in vitro anticancer activity of copper and zinc bisthiosemicarbazone complexes. Synthesis, characterization, and in vitro anticancer activity of copper and zinc bisthiosemicarbazone complexes.
Whole plant extracts ethanol extracted were prepared, coded as plant extract numbers 117, and tested for their potential as anticancer agents. In vitro antioxidant and anticancer activity of leea indica leaf. It is documented that medicinal herbs have rich anticancer potential, and on the forefront whenever we talk about anticancer remedies, are significant source of synthetic andor herbal origin. Chew et al 1999,evaluated the comparison of the anticancer activities of. Phytochemical testing showed the presence of alkaloids, flavonoids, tannins, saponins, terpenes, anthraquinones and steriods. Medicinal plants are playing an important role as a source of effective anticancer agents and it is significant that 60% of currently used anticancer agents are derived from natural sources including plants2.
In vitro studies of the anticancer action of tectaria. The antimicrobial activity of leaf extracts of four indigenous medicinal plants cassia auriculata, psidium guajava, carica papaya, and adathoda vasica, of families caesalpinaceae, solanaceae, caricaceae and acanthaceae were evaluated on four bacterial strains staphylococcus aureus mtcc 96, escherichia coli mtcc 738, enterobacter aerogenes mtcc 2990 and serratia marscens mtcc 2645. An overview article pdf available july 20 with 6,031 reads. Green tea, oligomeric procyanidins from grape seed and pine bark, bilberry, and ginkgo exhibited taa in the range of 5.
Rjpt invitro antimicrobial activity of four indigenous. The most active extracts were further screened on mcf7 cells by mtt assay. Pdf on jan 10, 2017, sadri said and others published in vitro anticancer activity of selected medicinal plants from oman find, read and cite all the research. The use of medicinal plants has a strong track record of contributing to drug development, and there is. In vitro and in vivo anticancer activity of copper bis. Dpph, frap, abts, phosphomolybdate assay and total reducing capability. Pdf anticancer activity of some medicinal plants from high altitude. Pdf in vitro evaluation of anticancer and antimicrobial. All these plants are potential candidates for in vivo studies since they are showing good in vitro anticancer activity. Screening of anticancer activity of selected medicinal plants. Sohail akhtar 1, afaf mohd weli 1, suleiman said alkhanjari 3 and qassim ahmed alriyami 1. In vitro and in vivo anticancer activity of root extracts.
As per national cancer 34 journal of medicinal plants studies institute nci, usa for anti cancer screening on a panel of human cell lines, an ic 50 value of less than 100. Human papiloma virus type 16 infected siha cervical cancer cell line were used to screen the anticancer potential of the extract of b. Sep 24, 2004 the plant extracts of 17 commonly used indian medicinal plants were examined for their possible regulatory effect on nitric oxide no levels using sodium nitroprusside as an no donor in vitro. Anticancer activity, medicinal plant, symplocos cochinchinensis, cancer cell lines 1. Screening of anticancer activity of selected medicinal. The process of identification and evaluation of cytotoxic molecules from plants can be achieved. Over time, cancer remains a world public health problem. Echoviruses, a serotype of enteroviruses, infect millions of people globally and there is no specific drug treatment or vaccine available for its management. In vitro antibacterial and anticancer activity of ziziphus mirza azim beg, uvs teotia and s farooq abstract according to ayurveda there are large numbers of traditional medicinal uses of ziziphus species and the reasons behind the medicinal potential of this plant are because of some allied substances such as. The anticancer activity of the different extracts of fruits of piper longum on human lung epithelial adenocarcinoma cell line hcc827 has been assessed in vitro using 34,5dimethylthiazol2yl2,5diphenyl tetrazolium bromide mtt assay. The methanolic extracts of forty species of plants traditionally used in saudi arabia for the treatment of a variety of diseases were tested. The plants were extracted with methanol and hot water.
Anticancer medicinal plants, indian origin, tumours, in vitro and in vivo methods. The screening of medicinal plants used locally for the treatment of infectious diseases, can provide a reliable option in the discovery of potent therapeutic compounds. In vitro studies of the anticancer action of tectaria cicutaria in human cancer cell lines. Anticancer potential of plants and natural products. In addition, the extracts were tested for their selectivity towards cancer cells as compared to normal cells. It might be expected to be a challenge to look at the saudi plants in order to discover new sources for new molecules which may have anticancer activity.
Pdf in vitro anticancer activity of selected medicinal plants from. Pdf in vitro and in vivo methods for anticancer activity. Invitro anticancer activity of boerhaavia diffusa linn. Anticancer properties of phytochemicals present in. In vitro antibacterial and anticancer activity of ziziphus.
Sohail akhtar1, afaf mohd weli1, suleiman said alkhanjari3 and qassim ahmed alriyami1 1school of pharmacy, college of pharmacy and nursing, university of nizwa, oman. Anthocephalus cadamba, aegle marmelos, emblica officinalis and moringa oleifera. In vitro anticancer activity of phytochemicals and extracts of medicinal plants cultured cancerderived cell lines with comparison to normal healthy cell lines are commonly used to assess the anticancer properties of isolated phytochemicals and extracts of medicinal plants table 2. Hence antioxidants play a very key role in the management of liver disorders and with respect to that antioxidant activity of all the selected medicinal. Several reports describe that the anticancer activity of medicinal plants is due to the presence of antioxidants present in them.
In vitro cytotoxic screening of selected saudi medicinal plants. In vitro anticancer activity of microbial isolates from. Plants have a long history of use in the treatment of cancer 11. Commonly used medicinal plant extracts with standardized content of polyphenols were investigated for their total antioxidant activity taa. Pdf in vitro anticancer activity of selected medicinal. The collected plants were then evaluated for cytoxicity. In vitro anticancer activity on du145 and pc3 human prostate cancer cell lines was evaluated by 34, 5dimethyl thiazole2yl2, 5diphenyl tetrazolium bromide mtt assay. In vitro antiinflammatory, anticancer and antioxidant activities. In vitro anticancer activity of aqueous extracts and ethanol extracts of fifteen traditional chinese medicines on human digestive tumor cell lines phytothe res, 21 2007, pp. Apoptosisinduced in vitro anticancer activity of methanolic extract of leaves and rhizomes of curcuma amada roxb.
Recent years have witnessed that there is a revival of interest in drug discovery from medicinal plants for the maintenance of health in all parts of the world. To evaluate anticancer activity of the barleria grandiflora acanthacae leaf on the. In vitro antioxidant and anticancer studies on the leaf of. The use of natural substances to inhibit carcinogenesis is a rapidly evolving aspect of cancer research. Modern research in the anticancer drug expansion from plants has been focused on investigate the molecular mechanism by.
Sansevieria liberica gerome and labroy agavaceae is a perennial plant widely distributed in tropical africa. Brenan was found to demonstrate potent anticancer activity in this study exhibiting ic50 0. In vitro and in vivo studies on selected medicinal plants. In vitro anticancer activity on du145 and pc3 human prostate cancer.
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